Tripotassium hexacyanoferrate

Acute Toxicity: inhalation

Administrative data

Endpoint:

acute toxicity: inhalation

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
The study does not need to be conducted because substance's particle size is for 100% >100 μm.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

November 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

other: ASTM D1921

Deviations:

not specified

GLP compliance:

no

Type of method:

sieving

Type of distribution:

mass based distribution

No.:

#1

Size:

>= 2 mm

Distribution:

0 %

No.:

#2

Size:

>= 1.4 mm

Distribution:

0.1 %

No.:

#3

Size:

>= 0.6 mm

Distribution:

43.4 %

No.:

#4

Size:

>= 0.4 mm

Distribution:

36.9 %

No.:

#5

Size:

>= 0.2 mm

Distribution:

19.3 %

No.:

#6

Size:

>= 0.15 mm

Distribution:

0.3 %

Conclusions:

In a sief test performed according to ASTM D1921, the particle size of Potassium ferricyanide was determined to be ≥ 0.15 mm. Particle sizes were distributed as follows: 43.4% ≥0.6 mm, 36.9% ≥0.4 mm and 19.3% ≥0.2 mm.