Registration Dossier
Registration Dossier
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EC number: 944-815-8 | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- Reaction product aqueous Phosphoric Acid, 1-Methoxypropan-2-ol and 4,4'-Isopropylidenediphenol-Epichlorohydrin
- EC Number:
- 944-815-8
- Molecular formula:
- Not possible to assign for a complex UVCB substance
- IUPAC Name:
- Reaction product aqueous Phosphoric Acid, 1-Methoxypropan-2-ol and 4,4'-Isopropylidenediphenol-Epichlorohydrin
- Test material form:
- liquid
Constituent 1
Results and discussion
Water solubilityopen allclose all
- Water solubility:
- >= 0.263 - <= 0.322 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Loading of aqueous phase:
- 0.3 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- >= 3.8 - <= 4
- Water solubility:
- >= 1.45 - <= 1.6 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Loading of aqueous phase:
- 3 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 2.9
- Details on results:
- Low nominal level:
The 24-hour measurement was significantly lower than the 48- and 72- hour measurements (maximum difference > 15%). Based on this, the water solubility of the water extractable constituents of the test item was given as the mean value of the 48- and 72-hour measurements. No test item was detected in the pretreated sample from the blank water mixture.
High nominal level:
The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15%. Based on this, the water solubility of the water extractable constituents of the test item is given as the mean value of the analyzed concentrations. No test item was detected in the pretreated sample from the blank water mixture.
Any other information on results incl. tables
Low nominal level (loading rate 1; 0.3 g/L)
Stirring time (Hours) |
Analysed concentration (g/L) | Mean (g/L) | Maximum difference (%) | pH |
| 24 | 0.263 | 0.310 | 7.6 | 3.9 |
| 48 | 0.299 | 3.8 | ||
| 72 | 0.322 | 4.0 |
High nominal level (loading rate 2; 3 g/L)
Stirring time (Hours) |
Analysed concentration (g/L) | Mean (g/L) | Maximum difference (%) | pH |
| 24 | 1.45 | 1.51 | 9.8 | 2.9 |
| 48 | 1.60 | 2.9 | ||
| 72 | 1.49 | 2.9 |
Applicant's summary and conclusion
- Conclusions:
- The water solubility value of the water extractable constituents of this complex UVCB (those that dissolved) at 20°C, was determined to be 0.310 to 1.51 g/L under the conditions of the test. In reality the procedure used removed many of the insoluble constituents and accordingly the aqueous solubility of the UVCB substance as a whole is likely to be much lower.
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