Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 29th, 2018 - February 2nd, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
column elution method
Key result
Water solubility:
0 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
>= 6.9 - <= 7.1
Details on results:
A negative result was obtained from the preliminary test.
5 samples were tested for the main test and a RSD of 12.7% was obtained.
Conclusions:
Based on the study results (i.e. water solubility equal to 3.21E-5 g/L), the substance is considered as "highly insuluble" in accordance with the ECHA guidance and "practically insoluble" in accordance with U.S. Pharmacopoeia.

Description of key information

The substance has a water solubility of 3.21E-5 g/L at 20°C.

Key value for chemical safety assessment

Water solubility:
0 g/L
at the temperature of:
20 °C

Additional information