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EC number: 476-670-7 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 733.33 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 6
- Conclusions:
- Solubilty of FeIDHA chelate in water is 733.33 g/dm3.
- Executive summary:
The subject of the task was the execution of study of solubility in water for chelate Fe(III)IDHA according to the OECD Test Guideline A6 (OECD 105). The method relied on the measurement of concentration of chelate (content of chelate) in solution tested with spectrophotometer based on calibration curves.
The following analysis was performed:
1. Initial study (sequential procedure)
2. Measurement of pH for samples using test-papers in water,
3. Determination of mass concentration of substance tested in water using the shake - flask method:
a) UV spectrum
b) Calibration curve
c) Measurement of concentration (contents) of the chelate with spectrophotometric method after 24h, 48h as well as 72h.
Solubility of Fe(III)IDHA chelate in water is 733.33 g/dm3.
Reference
Fe IDHA |
Result after 24h |
Result after 48h |
Result after 72h |
Concentration [mg/l] |
0.0122 |
0.0113 |
0.0117 |
Solubility [g/dm3] |
762.525 |
706.25 |
731.25 |
Average |
733.33 |
||
Difference between two last measurements |
3.4% |
||
The result between two most recent measurements is not different by more than 15% hence the result achieved is considered satisfactory.
Description of key information
Water solubility of Fe (III) IDHA determined according to OECD 105 is 733.33 g/L.
Key value for chemical safety assessment
- Water solubility:
- 733.33 mg/L
- at the temperature of:
- 20 °C
Additional information
The subject of the task was the execution of study of solubility in water for chelate Fe(III)IDHA according to the OECD Test Guideline A6 (OECD 105). The method relied on the measurement of concentration of chelate (content of chelate) in solution tested with spectrophotometer based on calibration curves.
The following analysis was performed:
1. Initial study (sequential procedure)
2. Measurement of pH for samples using test-papers in water,
3. Determination of mass concentration of substance tested in water using the shake - flask method:
a) UV spectrum
b) Calibration curve
c) Measurement of concentration (contents) of the chelate with spectrophotometric method after 24h, 48h as well as 72h.
Solubility of Fe(III)IDHA chelate in water is 733.33 g/dm3.
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