Sulfates of potassium, sodium and calcium, byproduct from fermentation

Oxidising properties

Administrative data

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04 May 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

-

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

calcium dipotassium disodium trisulfate

Molecular formula:

SO42-, K+, Na+, Ca2+

IUPAC Name:

calcium dipotassium disodium trisulfate

Test material form:

solid

Remarks:

light to beige solid

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: EXP LIberica Lote Al16503047
- Expiration date of the lot/batch: 30 November 2019
- Purity test date: 1 February 2017

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Controlled room temperature (15-25 deg Celsius, below 70% relative humidity) protected from light and humidity
- Stability under test conditions: not specified
- Solubility and stability of the test substance in the solvent/vehicle:not specified

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
The test item was ground to a fine powder before the application. Sufficient water was used to dampen the test material to ensure good contact with the skin.

Study design

Contact with:

powdered cellulose

Results and discussion

Test results (Oxidising solids)

Test results (Oxidising solids) 1

Key result

Sample tested:

reference mixture as specified

Remarks:

reference: 1:9 mixture baryum nitrate + cellulose

Parameter:

maximum burning rate

Result:

2.74 mm/s

Remarks on result:

other: burning with flame

Test results (Oxidising solids) 2

Key result

Sample tested:

test mixture as specified

Remarks:

1:9 sample-to-cellulose ratio

Parameter:

maximum burning rate

Result:

2.27 mm/s

Remarks on result:

other: burning with flame

Any other information on results incl. tables

Oxidiser cellulose-mixtures containing 10 to 90 % weight of oxidiser in 10 % increments were prepared. The details (contents of the mixtures and the ignition times) are summarized in Tables 1-2.

 

Table 1. Reference measurement

Ratio Ba(NO3)2: Cellulose	Weight Ba(NO3)2(g)	Weight Cellulose (g)	Ignition time (sec)	Burning rate (mm/sec)	Type of burning
10 : 90 %	2.00	18.00	73	2.74	burning with flame
20 : 80 %	4.00	16.00	80	2.50	burning with flame
30 : 70 %	6.00	14.00	82	2.44	burning with flame
40 : 60 %	12.00	18.00	89	2.25	burning with flame
50 : 50 %	15.00	15.00	107	1.87	burning with flame
60 : 40 %	18.00	12.00	148	1.35	burning with flame
70 : 30 %	14.00	6.00	171	1.17	burning with flame
80 : 20 %	16.00	4.00	ignited but did not propagate	-	burning with flame
90 : 10 %	45.00	5.00	not ignited	-	-

 

 

Table 2. Full Train Test

Ratio Test item : Cellulose	Weight Test item (g)	Weight Cellulose (g)	Ignition time (sec)	Burning rate (mm/sec)	Type of burning
10 : 90 %	2.00	18.00	120	1.67	burning with flame
20 : 80 %	4.00	16.00	161	1.24	burning with flame
30 : 70 %	6.00	14.00	195	1.03	burning with flame
40 : 60 %	12.00	18.00	208	0.96	burning with flame
50 : 50 %	15.00	15.00	ignited but did not propagate	-	-
60 : 40 %	18.00	12.00	ignited but did not propagate	-	-
70 : 30 %	14.00	6.00	ignited but did not propagate	-	-
80 : 20 %	16.00	4.00	not ignited	-	-
90 : 10 %	13.50	1.50	not ignited	-	-

 

The maximum burning rate is lower than the reference mixture therefore five parallel test was performed with the three mixtures which gave the fastest burning rate. The details are summarized in Table 3.

 

Table 3. Full Train Test

Ratio Test item : Cellulose	Weight Test item (g)	Weight Cellulose (g)	Ignition time (sec)	Burning rate (mm/sec)	Maximum burning rate (mm/sec)
10 : 90 %	4.00	36.00	90	2.22
			99	2.02
			91	2.20
			93	2.15
			91	2.20
			88	2.27
			94	2.13	2.27
20 : 80 %	8.00	32.00	112	1.79
			114	1.75
			111	1.80
			122	1.64
			120	1.67	1.80
30 : 70 %	12.00	28.00	151	1.32
			155	1.29
			168	1.19
			143	1.40
			169	1.18	1.40

 

The arithmetic mean of the burning rate with the 10:90 mixture is 2.17 mm/sec. The ±10% range is 1.95 – 2.39 mm/sec. The standard deviation is 0.0500 and the CV% is

2.28.

Applicant's summary and conclusion

Interpretation of results:

other: The test item has no oxidizing properties, according to the test method

Conclusions:

The maximum burning rate of the test item in different mixtures was found to be lower than the maximum burning rate of the reference mixture in the Full Train Test. Sulfates of potassium, sodium and calcium, by-product from fermentation has no oxidizing properties, according to the test method.

Executive summary:

The oxidising properties of the test item was assessed with a GLP-compliant study, following the standardised guideline EU method A.1.

The test item and cellulose is mixed in various ratios. Each mixture is then formed into a pile and the pile is ignited at one end. The maximum burning rate determined is compared with the maximum burning rate of reference mixture.

The maximum burning rate of the test item in different mixtures was found to be lower than the maximum burning rate of the reference mixture in the Full Train Test. Sulfates of potassium, sodium and calcium, by-product from fermentation has no oxidizing properties, according to the test method.