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Administrative data

Endpoint:
oxidising solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 May 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.17 (Oxidising Properties (Solids))
Version / remarks:
-
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Sulfates of potassium, sodium and calcium, byproduct from fermentation
Molecular formula:
SO42-, K+, Na+, Ca2+
IUPAC Name:
Sulfates of potassium, sodium and calcium, byproduct from fermentation
Test material form:
solid
Remarks:
light to beige solid
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: EXP LIberica Lote Al16503047
- Expiration date of the lot/batch: 30 November 2019
- Purity test date: 1 February 2017

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Controlled room temperature (15-25 deg Celsius, below 70% relative humidity) protected from light and humidity
- Stability under test conditions: not specified
- Solubility and stability of the test substance in the solvent/vehicle:not specified

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
The test item was ground to a fine powder before the application. Sufficient water was used to dampen the test material to ensure good contact with the skin.

Study design

Contact with:
powdered cellulose

Results and discussion

Test results (Oxidising solids)open allclose all
Key result
Sample tested:
reference mixture as specified
Remarks:
reference: 1:9 mixture baryum nitrate + cellulose
Parameter:
maximum burning rate
Result:
2.74 mm/s
Remarks on result:
other: burning with flame
Key result
Sample tested:
test mixture as specified
Remarks:
1:9 sample-to-cellulose ratio
Parameter:
maximum burning rate
Result:
2.27 mm/s
Remarks on result:
other: burning with flame

Any other information on results incl. tables

Oxidiser cellulose-mixtures containing 10 to 90 % weight of oxidiser in 10 % increments were prepared. The details (contents of the mixtures and the ignition times) are summarized in Tables 1-2.

 

Table 1. Reference measurement

Ratio

Ba(NO3)2: Cellulose

Weight

Ba(NO3)2(g)

Weight

Cellulose (g)

Ignition time (sec)

Burning rate (mm/sec)

Type of burning

10 : 90 %

2.00

18.00

73

2.74

burning with flame

20 : 80 %

4.00

16.00

80

2.50

burning with flame

30 : 70 %

6.00

14.00

82

2.44

burning with flame

40 : 60 %

12.00

18.00

89

2.25

burning with flame

50 : 50 %

15.00

15.00

107

1.87

burning with flame

60 : 40 %

18.00

12.00

148

1.35

burning with flame

70 : 30 %

14.00

6.00

171

1.17

burning with flame

80 : 20 %

16.00

4.00

ignited but did not propagate

-

burning with flame

90 : 10 %

45.00

5.00

not ignited

-

-

 

 

Table 2. Full Train Test

Ratio

Test item : Cellulose

Weight

Test item (g)

Weight

Cellulose (g)

Ignition time

(sec)

Burning rate (mm/sec)

Type of burning

10 : 90 %

2.00

18.00

120

1.67

burning with flame

20 : 80 %

4.00

16.00

161

1.24

burning with flame

30 : 70 %

6.00

14.00

195

1.03

burning with flame

40 : 60 %

12.00

18.00

208

0.96

burning with flame

50 : 50 %

15.00

15.00

ignited but did not propagate

-

-

60 : 40 %

18.00

12.00

ignited but did not propagate

-

-

70 : 30 %

14.00

6.00

ignited but did not propagate

-

-

80 : 20 %

16.00

4.00

not ignited

-

-

90 : 10 %

13.50

1.50

not ignited

-

-

 

The maximum burning rate is lower than the reference mixture therefore five parallel test was performed with the three mixtures which gave the fastest burning rate. The details are summarized in Table 3.

 

Table 3. Full Train Test

Ratio

Test item : Cellulose

Weight

Test item (g)

Weight

Cellulose (g)

Ignition time

(sec)

Burning rate (mm/sec)

Maximum burning rate (mm/sec)

10 : 90 %

4.00

36.00

90

2.22

 

 

 

 

99

2.02

 

 

 

 

91

2.20

 

 

 

 

93

2.15

 

 

 

 

91

2.20

 

 

 

 

88

2.27

 

 

 

 

94

2.13

2.27

20 : 80 %

8.00

32.00

112

1.79

 

 

 

 

114

1.75

 

 

 

 

111

1.80

 

 

 

 

122

1.64

 

 

 

 

120

1.67

1.80

30 : 70 %

12.00

28.00

151

1.32

 

 

 

 

155

1.29

 

 

 

 

168

1.19

 

 

 

 

143

1.40

 

 

 

 

169

1.18

1.40

 

The arithmetic mean of the burning rate with the 10:90 mixture is 2.17 mm/sec. The ±10% range is 1.95 – 2.39 mm/sec. The standard deviation is 0.0500 and the CV% is

2.28.

Applicant's summary and conclusion

Interpretation of results:
other: The test item has no oxidizing properties, according to the test method
Conclusions:
The maximum burning rate of the test item in different mixtures was found to be lower than the maximum burning rate of the reference mixture in the Full Train Test. Sulfates of potassium, sodium and calcium, by-product from fermentation has no oxidizing properties, according to the test method.
Executive summary:

The oxidising properties of the test item was assessed with a GLP-compliant study, following the standardised guideline EU method A.1.

The test item and cellulose is mixed in various ratios. Each mixture is then formed into a pile and the pile is ignited at one end. The maximum burning rate determined is compared with the maximum burning rate of reference mixture.

The maximum burning rate of the test item in different mixtures was found to be lower than the maximum burning rate of the reference mixture in the Full Train Test. Sulfates of potassium, sodium and calcium, by-product from fermentation has no oxidizing properties, according to the test method.

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