Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
7 - 9 February 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: OPPTS 830.7840, OECD 105, EC Method A.6 and CIPAC MT 181
Version / remarks:
Preliminary test based on visual assessment of the solubility of the test substance in water and n-octanol separately.
GLP compliance:
yes
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Batch No. of test material: R134-2
- Appearance: Tan-light brown opaque liquid
- Expiration date of the batch: 17 July 2018
- Storage condition of test material: Stored frozen at -80°C
- Stability under test conditions: Test substance was expected to be stable for the duration of testing
Key result
Type:
log Pow
Partition coefficient:
-2.4
Temp.:
20 °C
pH:
>= 6 - <= 8
Details on results:
Water solubility: 37.5 g/L
Octanol solubility: 0.15 g/L
Pow: 0.004
log Pow: -2.40
Conclusions:
The partition coefficient (log Pow) of the test item, Harpin-ab Fermentation Extract, was -2.40.

Description of key information

The partition coefficient (log Pow) of the test item, Harpin-ab Fermentation Extract, was determined using an estimation method based on the solubility ratio of the test substance in water and n-octanol and was found to be -2.40.

Key value for chemical safety assessment

Log Kow (Log Pow):
-2.4
at the temperature of:
20 °C

Additional information