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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-11-29 - 2018-11-30
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
12.5 µm
St. dev.:
0.13
Remarks on result:
other: average of two test series
Percentile:
D10
Mean:
4.7 µm
St. dev.:
0.02
Remarks on result:
other: average of two test series
Percentile:
D90
Mean:
27.7 µm
St. dev.:
0.23
Remarks on result:
other: average of two test series
Conclusions:
The test substance has a median particle size D50 = 12.5 µm.
Executive summary:
The particle size distribution of the test substance 2-Hydroxy-1-[4-(4-(2-hydroxy-2-methylpropionyl)phenoxy)phenyl]-2-methylpropan-1-one was determined by laser light scattering, according to OECD Guideline 110 (and OPPTS 830.7520 and ISO 13320). The test substance has a median particle size D50 = 12.5 µm.

Description of key information

The particle size distribution of the test substance was determined by laser diffraction according to OECD Guideline 110 and ISO Method 13320, 2009 (Schiewer, 2019).

Additional information

Median particle size D50 = 12.5 µm