Registration Dossier
Registration Dossier
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EC number: 253-042-9 | CAS number: 36451-09-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- calculation
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Guideline:
- other: QSAR
- Specific details on test material used for the study:
- chemical structure was used as input
- Key result
- Parameter:
- half-life in days (QSAR/QSPR)
- Value:
- > 28
- Sampling time:
- 28 d
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
- Details on results:
- CAS Number:
SMILES : CLS(=O)(=O)C1=CC(=N#N)C(=O)c2ccccc12
CHEM :
MOL FOR: C10 H5 CL1 N2 O3 S1
MOL WT : 268.68
--------------------------------- Biowin Summary ----------------------------------------------
Probability of Rapid Biodegradation (BIOWIN v4.10):
Biowin1 (Linear Model) : 0.6265
Biowin2 (Non-Linear Model) : 0.2211
Expert Survey Biodegradation Results:
Biowin3 (Ultimate Survey Model): 2.5830 (weeks-months)
Biowin4 (Primary Survey Model) : 3.4379 (days-weeks )
MITI Biodegradation Probability:
Biowin5 (MITI Linear Model) : 0.0604
Biowin6 (MITI Non-Linear Model): 0.0258
Anaerobic Biodegradation Probability:
Biowin7 (Anaerobic Linear Model): -0.4488
Ready Biodegradability Prediction: NO - Interpretation of results:
- not readily biodegradable
Reference
Description of key information
Based on QSAR calculation, the test item is not considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
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