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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-01-29 to 2018-06-14
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
18.85 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
200 mg/L
Incubation duration:
24 h
Temp.:
19.7 °C
pH:
7
Details on results:
Elongated dissolution durations (>24 h) did not lead to an increase in measured concentrations of test substance.
Conclusions:
The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was measured to be 18.85±0.40 mg/L (at 19.7°C and pH 7)
Executive summary:

The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was determined according to the flask method described in the OECD Guideline 105 (1995).

Therefore, the test substance was shaken in deionized water at 30°C (for 24, 48 and 72 h) and equilibrated afterwards at 20°C for further 24 h.

Adsorption of the test item to the test vials was avoided by the use of 250-mL PFA bottles. The obtained samples were measured using HPLC.

The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was determined to be:

Water solubility = 18.85±0.40 mg/L (at 19.7°C and pH 7 after 24 hours).

Elongated dissolution durations (>24 h) did not lead to an increase in measured concentrations of test substance.

Description of key information

The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was measured to be 18.85±0.40 mg/L (at 19.7°C and pH 7)

Key value for chemical safety assessment

Water solubility:
18.85 mg/L
at the temperature of:
19.7 °C

Additional information

The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was determined according to the flask method described in the OECD Guideline 105 (1995).

Therefore, the test substance was shaken in deionized water at 30°C (for 24, 48 and 72 h) and equilibrated afterwards at 20°C for further 24 h.

Adsorption of the test item to the test vials was avoided by the use of 250-mL PFA bottles. The obtained samples were measured using HPLC.

The water solubility of octadecanoic acid, reaction products with acetic acid and tetraethylenepentamine was determined to be:

Water solubility = 18.85±0.40 mg/L (at 19.7°C and pH 7 after 24 hours).

Elongated dissolution durations (>24 h) did not lead to an increase in measured concentrations of test substance.