4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

26.07.2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions

GLP compliance:

no

Type of method:

Laser scattering/diffraction

Key result

Percentile:

D50

Mean:

69 µm

Remarks on result:

other: no SD indicated

Key result

Percentile:

D10

Mean:

12 µm

Remarks on result:

other: no SD indicated

Key result

Percentile:

D90

Mean:

241 µm

Remarks on result:

other: no SD indicated

The test item consisted of transparent particles which appear needle-shaped. The particles strongly agglomerate.

The particles were introduced to the analyser beam by the dry powder feeder by direct spraying through the measurements area. The powder was loosened by an integrated vibrator. The particles were dispersed and fed to the optical system by pressurized dry air (1,5 bar_g). After passing the analyser beam the sample was collected in a vacuum cleaner.

After adjusting the laser, measuring the background and adjusting the correct particle concentration (obscuration) the measurement was started. The control software automatically performed three measurements. The average of these three measurements was given as result. Two test series of three measurements each were performed. The measurement time was 8 s. Median values were calculated from unrounded values.

The median particle size L50 (D (v, 0.5): 50 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L50 = 70.6 μm

2nd test series: L50 = 68.7 μm

The average of the median particle size L50 was: L50 = 69.6 μm

The particle size L10 (D (v, 0.1 ): 10 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L10 = 12.2 μm

2nd test series: L10 = 11.6 μm

The average of the particle size L10 was: L10 = 11.9 μm

The particle size L90 (D (v, 0.9): 90 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L90 = 242.2 μm

2nd test series: L90 = 241.4 μm

The average of the particle size L90 was: L90 = 241.8 μm

The particle size distribution showed a monomodal distribution with a shoulder. The maximum was observed at approximately 80 µm and a shoulder at approximately 3 µm. The second measurement showed a second shoulder at approximately 1000 µm.

 

Conclusions:

The median particle size L50 of the test item deduced from the particle size distributions was 69 μm.

Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 69 µm.

Description of key information

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 69 µm.