Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
4,4'-Methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol
Status:
67/548/EEC self classification

Classification

Explosiveness

Reason for no classification:
conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
conclusive but not sufficient for classification

Flammability

Reason for no classification:
conclusive but not sufficient for classification

Thermal stability

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity

Classification:
Xn; R20 Harmful by inhalation.

Acute toxicity - irreversible damage after single exposure

Reason for no classification:
conclusive but not sufficient for classification

Repeated dose toxicity

Classification:
Xn; R48/20 Harmful: danger of serious damage to health by prolonged exposure through inhalation.

Irritation / corrosion

Classification:
Xi; R36/37/38 Irritating to eyes, respiratory system and skin.

Sensitisation

Classification:
R42/43 May cause sensitisation by inhalation and skin contact.

Carcinogenicity

Classification:
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.

Mutagenicity - genetic toxicity

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - fertility

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - development

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - breastfed babies

Reason for no classification:
conclusive but not sufficient for classification

Environment

Reason for no classification:
conclusive but not sufficient for classification

Labelling

Indication of danger

Xn - harmful

Risk phrases

R20 - Harmful by inhalation
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect
R42/43 - May cause sensitisation by inhalation and skin contact
R48/20 - Harmful: danger of serious damage to health by prolonged exposure through inhalation

Safety phrases

S38 - in case of insufficient ventilation, wear suitable respiratory equipment
S1/2 - keep locked up and out of reach of children
S23 - do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S36/37 - wear suitable protective clothing and gloves
S45 - in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)

Specific concentration limits

1. Concentration range (%):
> 5
Classification:
Xi; R36/37/38 Irritating to eyes, respiratory system and skin.
2. Concentration range (%):
> 0.1
Classification:
R42 May cause sensitisation by inhalation.

Notes

Note C
Note 2