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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
no
Type of method:
thermal analysis
Key result
Melting / freezing pt.:
>= 89 - <= 98 °C
Atm. press.:
1 015 hPa
Sublimation:
no

During the first heating period of the main DSC test several overlapping endothermic signals are recorded over a temperature range of 30 … 80 °C. This may be related to an irregular composition of the main component and the side products in the original sample (polymorphism; mixture).

After thermal conditioning at -20 °C at the end of the first cooling step reversible endothermic effects in the range of 89 °C (extrapolated onset) and 98 °C (extrapolated endset) were recorded. The corresponding exothermic effects are detected in the range of 54 °C (extrapolated onset) and 42 °C (extrapolated endset).

This stability and reversibility of these results point to melting and delayed re-freezing processes. Due to the broad temperature range at which the melting process was detected a defined melting point may not be assessable, which can be explained by the inhomogeneity of the test item. Thus, a melting range of 89 °C - 98 °C is reported instead.

Conclusions:
Due to the broad temperature range at which the melting process was detected in the DSC experiment a defined melting point may not be assessable. Thus, a melting range of 89 °C - 98 °C is reported instead.
Executive summary:

The melting point of the substance was determined according to OECD guideline 102 by using Differential Scanning Calorimetry (DSC). After thermal conditioning at -20 °C at the end of the first cooling step reversible endothermic effects in the range of 89 °C (extrapolated onset) and 98 °C (extrapolated endset) were recorded. The corresponding exothermic effects are detected in the range of 54 °C (extrapolated onset) and 42 °C (extrapolated endset).

This stability and reversibility of these results point to melting and delayed re-freezing processes. Due to the broad temperature range at which the melting process was detected a defined melting point may not be assessable, which can be explained by the inhomogeneity of the test item. Thus, a melting range of 89 °C - 98 °C is reported instead.

Description of key information

melting range: 89°C - 98°C; OECD Guideline 102; RL1; no GLP 

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
89 °C

Additional information

The melting point of C16 Alkylamidopropyltrimethylammonium Chloride was determined in two experiments. In the melt microscope the test item changes at an onset-temperature of 80 °C, at 150 °C approximately half of the product is “melted”.

In the DSC experiment reversible endothermic effects in the range of 89 °C (extrapolated onset) and 98 °C (extrapolated end) were recorded.