Phenol, 4,4'-(1-methylethylidene)bis[2,6-dibromo-, polymer with 2-(chloromethyl)oxirane and 4,4'-(1-methylethylidene)bis[phenol], Ph ethers

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Deviations:

no

GLP compliance:

yes

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

>= 3.34 - <= 6.5

Temp.:

25 °C

pH:

ca. 7.9

Conclusions:

The partition coefficient of the test item has been determined to be in the range 2.58 to 7.68 x 104, log10 Pow of 0.41 to 4.89. For approximately 88% of the test item by peak area normalisation the partition coefficient was in the range 2.58 to 144, log10 Pow of 0.41 to 2.16.

Executive summary:

In the range 2.58 to 7.68 x 104, log10 Pow of 0.41 to 4.89, using the HPLC method, designed to be compatible with Method A.8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 117 of the OECD Guidelines for Testing of Chemicals, 13 April 2004.

For approximately 88% of the test item by peak area normalisation the partition coefficient was in the range 2.58 to 144, log10 Pow of 0.41 to 2.16.

Description of key information

Overall log10 Pow: In the range 3.55 to >6.5

The partition coefficient of the test item has been determined to be in the range 172 to greater than 3.16 x 106, log10 Pow in the range 2.24 to greater than 6.5.