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EC number: 418-220-4 | CAS number: -
No long-term studies were available. Available short term studies showed LC50 (96h) on fish > 100 mg/l, EC50 (48h) on daphnia > 100 mg/l and EC50 (72h) on algae > 100 mg/l, as nominal concentrations. Therefore, the concentration of 100 mg/l was used in the calculation of PNEC water .
Assessment factors of 1000 and 10000 were used for fresh water and marine water, respectively.
The derivation of PNECwater, intermittent was done by applying an assessment factor of 100.
The value of PNECstp was derived using 100 mg/l derived from a toxicity study to microorganisms where the EC50 > 100 mg/l was observed.
Due to the lack of ecotoxicological data, PNECsediment for fresh water and marine water were calculated using equilibrium partitioning method. This method uses PNECwater for aquatic organisms and suspended matter/water partition coefficients as inputs. Bulk density of wet suspended matter is 1150 kg/m3. Note that this approach is used only as a rough screening since it may result in both an overestimation or underestimation of toxicity. The suspended matter-water partition coefficient was computed and resulted as 0.979 m3/m3. A correction factor of 4.6 from wet weight to dry weigth was applied to obtain the final PNECsediment.
The amount of test substance in the air compartment was expected to be very low, since the substance is a solid with a negligible vapour pressure. Therefore, no hazard was identified.
The calculation of PNECsoil was done using the equilibrium partitioning method, based on the assumption that soil toxicity, expressed in terms of freely-dissolved substance concentration in the pore water, is the same as aquatic toxicity. The pore water concentration is correlated with the bioavailable fraction. Note that this approach was originally developed for sediments but it may be applied to soil. In the calculation of PNECsoil, PNECwaterfor aquatic organisms and soil-water partition coefficient were used as inputs. Bulk density of wet soil is 1700 kg/m3. Soil-water partition coefficient was computed and resulted as 0.295 m3/m3. A correction factor of 1.13 from wet weight to dry weight was applied to obtain the final PNECsoil.
Secondary poisoning concerns toxic effects in the higher members of the food chain which results from ingestion of organisms from lower trophic levels that contain accumulated substances. It is relevant for highly lipophilic organic chemicals, with a log Pow above the cutoff value of 4 reported in the CLP Regulation (EC 1272/2008). Due to the absence of potential for bioaccumulation indicated by a log Pow of -2.9, test substance was considered as not hazardous with respect to secondary poisoning.
According to the CLP Regulation (EC n. 1272/2008), Part 4: Environmental Hazards, the substances can be classified for hazardous to the aquatic environment when the following criteria are met:
A )Acute (short-term) aquatic hazard Category Acute 1: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) ≤ 1 mg/L.
B) Long-term aquatic hazard
(i) Non-rapidly degradable substances for which there are adequate chronic toxicity data available:
Category Chronic 1: Chronic NOEC or ECx (for fish) and/or Chronic NOEC or ECx (for crustacea) and/or Chronic NOEC or ECx (for algae or other aquatic plants)≤0,1 mg/L
Category Chronic 2: Chronic NOEC or ECx (for fish) and/or Chronic NOEC or ECx (for crustacea) and/or Chronic NOEC or ECx (for algae or other aquatic plants)≤1 mg/L.
(iii) Substances for which adequate chronic toxicity data are not available and the substance is not rapidly degradable and/or the experimentally determined BCF ≥ 500 (or, if absent, the log K ow ≥ 4).
Category Chronic 1: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) ≤ 1 mg/L
Category Chronic 2: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants)> 1 to ≤10 mg/L
Category Chronic 3:96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) > 10 to ≤ 100 mg/L.
The substance is not rapidly degradable and the available short-term toxicity tests to fish, invertebrate and algae fixed the effect levels that do not meet the criteria fo Aquatic toxicity. However, the substance is listed in Annex VI of CLP regulation (EC 1272/2008) and is classfied as Aquatic Chronic 3.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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