Registration Dossier
Registration Dossier
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EC number: 688-270-1 | CAS number: 16133-25-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- not specified
- Remarks:
- migrated information
- Adequacy of study:
- weight of evidence
- Study period:
- 1960-1983
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Limited study details provided. Data presented as abstract.
- Justification for type of information:
- Limited study details provided. Data presented as abstract.
Data source
Reference
- Reference Type:
- publication
- Title:
- The Acute Oral Toxicity, Repellency, and Hazard Potential of 998 Chemicals to One or More Species of Wild and Domestic Birds
- Author:
- Schafer EW, Bowles WA, and Hurlbut J
- Year:
- 1 983
- Bibliographic source:
- Arch. Environm. Con tam. Toxicol. 12, 355-382 ( 1983)
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The acute oral toxicity of test substance to two species of wild and domestic birds were determined by standardized testing procedures.
- GLP compliance:
- not specified
- Test type:
- other: LD50- estimation
- Limit test:
- no
Test material
- Reference substance name:
- Pyridine-3-sulphonic acid
- EC Number:
- 211-265-9
- EC Name:
- Pyridine-3-sulphonic acid
- Cas Number:
- 636-73-7
- Molecular formula:
- C5H5NO3S
- IUPAC Name:
- pyridine-3-sulfonic acid
- Test material form:
- not specified
- Details on test material:
- - Name of test material: 3-Pyridylsulfonic acid
- Molecular formula: C5-H5-N-O3-S
- Molecular weight: 159.165
- Smiles notation: S(c1cnccc1)(=O)(=O)O
- Substance type: Pure active substance
- Other: The chemicals included technical and analytical grade, pesticidal, pharmaceutical and other commercial or experimental compounds that were either purchased or solicited from cooperating firms.
No further details were provided in the publication
Constituent 1
Test animals
- Species:
- other: Wild and domestic birds (Red winged blackbird and Coturnix Quail)
- Strain:
- other: Agelaius phoeniceus and Coturnix coturnix
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Source: Wildlife Research Center, Denver, Colorado
- Acclimation period: Wild-trapped birds were preconditioned to captivity for 2 to 6 weeks
No further details on test animal were provided
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- polyethylene glycol
- Details on oral exposure:
- No details were provided in the publication
- Doses:
- No details were provided in the publication
- No. of animals per sex per dose:
- No details were provided in the publication
- Control animals:
- not specified
- Details on study design:
- No details were provided in the publication
- Statistics:
- No details were provided in the publication
Results and discussion
- Preliminary study:
- no
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 100 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: study on red winged blackbird
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 316 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: study on coturnix quail
- Mortality:
- No details were provided in the publication
- Clinical signs:
- other: No details were provided in the publication
- Gross pathology:
- No details were provided in the publication
- Other findings:
- No details were provided in the publication
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Remarks:
- migrated information
- Conclusions:
- Under the study conditions, LD50 of test substance was determined to be in range of 100 - 316 mg/kg bw
- Executive summary:
The acute oral toxicity of test substance to two species of wild and domestic birds were determined by standardized testing procedures. Under the study conditions, LD50 of test substance was determined to be in range of 100 - 316 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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