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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
november-december 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
-0.4
Temp.:
20 °C
pH:
7
Conclusions:
The substance 3-methylsulfolane has a Log Pow of -0.4 at neutral pH and 20ºC.
Executive summary:

The substance 3 -methylsulfolane has a Log Pow of -0.4 at neutral pH and 20ºC according to the regulations OECD 107, EU Method A.8 and OPPTS 830.7550 by the shake flask method.

Description of key information

3 -Methylsulfolane has a Log Pow of -0.4 at neutral pH and 20ºC.

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.4
at the temperature of:
20 °C

Additional information