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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: no specified
- Expiration date of the lot/batch: no specified
- Purity test date: pure (99%)

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
not specified

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
not specified
Analytical monitoring:
yes
Details on sampling:
No specified
Vehicle:
no
Details on test solutions:
PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: not specified
- Controls: Concurrent control
Test organisms (species):
Pimephales promelas
Details on test organisms:
TEST ORGANISM
- Common name: Pimephales (bluntnose minnows)
- Strain: Cypriniformes (minnows, suckers)
- Source: Laboratory
- Age at study initiation (mean and range, SD): 30 days
- Length at study initiation (length definition, mean, range and SD): not specified
- Weight at study initiation (mean and range, SD): not specified
- Method of breeding: not specified
- Maintenance of the brood fish: not specified

ACCLIMATION
not specified

FEEDING DURING TEST
not specified
Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Hardness:
44.8 milligrams per liter Calcium carbonate
Test temperature:
24.9
pH:
7.54
Dissolved oxygen:
6.2 mg/L
Salinity:
50 milligrams per liter Calcium carbonate
Conductivity:
Not specified
Nominal and measured concentrations:
6 doses
Details on test conditions:
Not specified
Reference substance (positive control):
not specified
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 4.55 - < 5.38 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
behaviour
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
behaviour
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 4.75 - < 6 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
behaviour
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
> 4.55 - < 5.38 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
behaviour
Details on results:
Not specified
Results with reference substance (positive control):
Not specified
Validity criteria fulfilled:
yes
Conclusions:
The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6] mg/L.
Executive summary:

The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6[ mg/L.

Description of key information

The LC50, 48h for 4-phenoxyphenol is ]4.75 - 6[ mg/L.

Key value for chemical safety assessment

LC50 for freshwater fish:
4.8 mg/L

Additional information