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EC number: 813-120-0 | CAS number: 1262967-45-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 July 2011 - 09 February 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Study was conducted in accordance with International guidelines and GLP. All guideline validity criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 11 July 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Commission Regulation (EC) No 440/2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Specific details on test material used for the study:
- RADIOLABELLING INFORMATION (if applicable)
- Radiochemical purity: N/A
- Specific activity: N/A
- Locations of the label: N/A
- Expiration date of radiochemical substance: N/A
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature in the dark and under nitrogen.
- Stability under test conditions: Assumed stable.
- Solubility and stability of the test substance in the solvent/vehicle: N/A, applied as supplied.
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: N/A
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: N/A
- Preliminary purification step (if any): N/A
- Final dilution of a dissolved solid, stock liquid or gel: N/A
- Final preparation of a solid: N/A
FORM AS APPLIED IN THE TEST (if different from that of starting material): Applied as supplied.
TYPE OF BIOCIDE/PESTICIDE FORMULATION (if applicable): N/A
OTHER SPECIFICS: No - Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The test substance, Tetraesters of pentaerythritol with 2- methylpropanoic acid and 3,5,5-trimethyl-hexanoic acid, was found to have a vapour pressure of 2 x 10-4 Pa at 25 °C.
- Executive summary:
OECD 104 (2012) - The vapour pressure was determined using a vapour pressure balance.
A quantity of test substance (1.5 g) was added to the furnace, the apparatus assembled and evacuated to a pressure of less than 1 x 10-5Torr (1.3 x 10-3Pa).
After stabilisation at a given temperature, the shutter was opened to allow a stream of vapour to impact upon one balance pan. The temperature and pan deflection were recorded on a chart recorder. The trace obtained enabled the calculation of mass difference. The furnace temperature was then raised in steps of approximately 5 ºC and further measurements taken.
Two definitive runs were performed between temperatures of 33 and 77 °C, the pressure being kept at less than 1 x 10-5 Torr (1.3 x 10-3 Pa) throughout. Initial runs were disregarded, the high and variable results being indicative of degassing and/or removal of volatile impurities. Mass differences, condensation rates and the sample temperature were monitored on a chart recorder on every occasion that the shutter was opened.
The test substance, Tetraesters of pentaerythritol with 2-methylpropanoic acid and 3,5,5-trimethyl-hexanoic acid, was found to have a vapour pressure of 2 x 10-4 Pa at 25 °C.
Reference
Table 1 Determination of vapour pressure (run 1)
Temperature (ºC) |
Mass difference (µg) |
Condensation rate (µg/s) |
Vapour pressure (Pa) |
a |
Corrected vapour pressure (Pa) |
1/Temperature (1/K) |
Log vapour pressure |
||
From mass difference |
From condensation |
From mass difference |
From condensation |
||||||
33.5 |
0.14 |
0.007 |
0.00022 |
0.00021 |
0.633 |
0.00033 |
0.00033 |
0.00326 |
-3.48 |
38.5 |
0.40 |
0.007 |
0.00066 |
0.00021 |
0.277 |
0.00076 |
0.00076 |
0.00321 |
-3.12 |
43.0 |
0.71 |
0.011 |
0.00117 |
0.00031 |
0.231 |
0.00132 |
0.00132 |
0.00316 |
-2.88 |
47.5 |
1.17 |
0.020 |
0.00194 |
0.00057 |
0.257 |
0.00222 |
0.00222 |
0.00312 |
-2.65 |
53.0 |
1.98 |
0.044 |
0.00327 |
0.00129 |
0.330 |
0.00391 |
0.00391 |
0.00307 |
-2.41 |
57.5 |
2.80 |
0.072 |
0.00461 |
0.00213 |
0.375 |
0.00567 |
0.00567 |
0.00302 |
-2.25 |
62.5 |
3.73 |
0.137 |
0.00615 |
0.00409 |
0.499 |
0.00819 |
0.00819 |
0.00298 |
-2.09 |
67.5 |
5.01 |
0.218 |
0.00826 |
0.00656 |
0.569 |
0.01154 |
0.01154 |
0.00294 |
-1.94 |
72.0 |
6.52 |
0.353 |
0.01076 |
0.01066 |
0.663 |
0.01609 |
0.01609 |
0.00290 |
-1.79 |
76.5 |
8.04 |
0.475 |
0.01325 |
0.01444 |
0.705 |
0.02048 |
0.02048 |
0.00286 |
-1.69 |
Table 2 Determination of vapour pressure (run 2)
Temperature (ºC) |
Mass difference (µg) |
Condensation rate (µg/s) |
Vapour pressure (Pa) |
a |
Corrected vapour pressure (Pa) |
1/Temperature (1/K) |
Log vapour pressure |
||
From mass difference |
From condensation |
From mass difference |
From condensation |
||||||
33.5 |
0.14 |
0.007 |
0.00022 |
0.00019 |
0.600 |
0.00032 |
0.00032 |
0.00326 |
-3.49 |
38.5 |
0.38 |
0.008 |
0.00062 |
0.00023 |
0.309 |
0.00074 |
0.00074 |
0.00321 |
-3.13 |
43.0 |
0.72 |
0.011 |
0.00118 |
0.00032 |
0.235 |
0.00134 |
0.00134 |
0.00317 |
-2.87 |
47.5 |
1.20 |
0.022 |
0.00198 |
0.00064 |
0.277 |
0.00230 |
0.00230 |
0.00312 |
-2.64 |
53.0 |
1.81 |
0.033 |
0.00298 |
0.00096 |
0.278 |
0.00346 |
0.00346 |
0.00307 |
-2.46 |
57.5 |
2.54 |
0.063 |
0.00419 |
0.00188 |
0.366 |
0.00513 |
0.00513 |
0.00302 |
-2.29 |
62.5 |
3.81 |
0.129 |
0.00627 |
0.00384 |
0.469 |
0.00820 |
0.00820 |
0.00297 |
-2.09 |
67.5 |
4.85 |
0.209 |
0.00800 |
0.00627 |
0.563 |
0.01114 |
0.01114 |
0.00294 |
-1.95 |
72.0 |
6.17 |
0.325 |
0.01018 |
0.00983 |
0.651 |
0.01509 |
0.01509 |
0.00290 |
-1.82 |
76.5 |
8.93 |
0.556 |
0.01473 |
0.01691 |
0.729 |
0.02318 |
0.02318 |
0.00286 |
-1.63 |
Description of key information
Vapour pressure = 2 x 10-4 Pa at 25 ºC; OECD 104; Sydney, P. (2012)
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
OECD 104 (2012) - The vapour pressure was determined using a vapour pressure balance.
A quantity of test substance (1.5 g) was added to the furnace, the apparatus assembled and evacuated to a pressure of less than 1 x 10-5Torr (1.3 x 10-3Pa).
After stabilisation at a given temperature, the shutter was opened to allow a stream of vapour to impact upon one balance pan. The temperature and pan deflection were recorded on a chart recorder. The trace obtained enabled the calculation of mass difference. The furnace temperature was then raised in steps of approximately 5 ºC and further measurements taken.
Two definitive runs were performed between temperatures of 33 and 77 °C, the pressure being kept at less than 1 x 10-5 Torr (1.3 x 10-3 Pa) throughout. Initial runs were disregarded, the high and variable results being indicative of degassing and/or removal of volatile impurities. Mass differences, condensation rates and the sample temperature were monitored on a chart recorder on every occasion that the shutter was opened.
The test substance, Tetraesters of pentaerythritol with 2- methylpropanoic acid and 3,5,5-trimethyl-hexanoic acid, was found to have a vapour pressure of 2 x 10-4 Pa at 25 °C.
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