Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the physicochemical and toxicological properties suggest no potential for a significant rate of absorption through the skin
Justification for type of information:
The test substance has acute oral toxicity >5000 mg/kg bodyweight, the acute dermal LD50 can therefore be assumed to also be greater than 5000mg/kg bodyweight as dermal absorption is not expected to exceed oral absorption due to it high water solubility. Therefore testing for acute dermal toxicity is waived as not scientifically justified.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion