Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available
Dose descriptor:
LD50
Value:
1 591 mg/kg bw

Additional information

Justification for classification or non-classification

Acute Oral Toxicity effects, rats:

Male: LD50 1591 (1348 -1847) mg/kg bw, Max mortality 24h

Female: LD50 1327 (1071 -1562) mg/ kg bw, Max mortality 4.5h

Data source: Product Monograph PrZOLOFT® (sertraline hydrochloride) Pfizer Canada Inc. Submission Control No: 170223 27 January 2014 Ks:4