(2E)-2-methyl-3-(4-methylphenyl)prop-2-en-1-ol

Appearance / physical state / colour

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

appearance / physical state / colour

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

06-12-2010 to 16-12-2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Visual observation of physical state and appearance by the testing laboratory

Reason / purpose for cross-reference:

reference to same study

Qualifier:

no guideline required

Principles of method if other than guideline:

Visual observation of physical state and appearance by the testing laboratory

GLP compliance:

yes (incl. QA statement)

Remarks:

inspected: May 2009; signature: July 2009

Physical state at 20°C and 1013 hPa:

solid

Remarks:

The test item was described as a 'colourless liquid' at the start of testing for Melting/Freezing Point. The test item was observed to freeze (solid) at 22.6 ± 0.5 °C.

Form:

solid

Colour:

colourless liquid at the start of testing. Description of the test item upon freezing was not reported.

Substance type:

organic

Conclusions:

The physical state and appearance of the test item was evaluated by visual observation. The test item was determined to be a colourless liquid prior to testing. In the Melting/Freezing Point study the test item was observed to freeze at freeze (solid) at 22.6 ± 0.5 °C.

Executive summary:

The appearance of the test item has been determined as:

Form: liquid and that was observed to freeze solid at 22.6 ± 0.5°C (liquid that may crystallize or solidify)

Colour: colourless

Reference 2

Endpoint:

appearance / physical state / colour

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

30-09-2011 to 12-10-2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Visual observation of physical state and appearance by the testing laboratory

Reason / purpose for cross-reference:

reference to same study

GLP compliance:

yes (incl. QA statement)

Remarks:

inspected: March 2011; signature: May 2011

Specific details on test material used for the study:

The physical state and appearance of the test material were evaluated by visual observation. The test item was determined to be a clear colourless liquid at temperature > 23°C (determined by the laboratory). The test item was a white waxy solid at temperature < 23°C.

Physical state at 20°C and 1013 hPa:

solid

Form:

solid

Remarks:

was a white waxy solid at temperature < 23°C and a clear colourless liquid at temperature > 23°C

Colour:

white waxy

Substance type:

organic

Conclusions:

The physical state and appearance of the test item was evaluated by visual observation. The test item was determined to be a white waxy solid. The test item was observed to melt to a clear colourless liquid at > 23°C.

Executive summary:

The appearance of the test item has been determined as:

Form: waxy solid

Colour: white

Applicant assessment indicates: that the test item may demonstrate some "liquid-crystal" behaviour with an intermediary phase below the melting point where a "pasty" liquid may be observed just below the isotropic phase (molten liquid), based on expert judgement and the weight of evidence. There was clear evidence of crystallization prior to the study. The substance was observed to melt at > 23°C (determined by the laboratory). The test item was a white waxy solid at temperature < 23°C.

Description of key information

Weight of evidence: State of the substance at 20 °C and 101.3 kPa: white waxy solid < 20 °C and a clear colourless liquid at temperatures > 23 °C, 2018

Key value for chemical safety assessment

Physical state at 20°C and 1013 hPa:

solid

Additional information

The weight of evidence is that the test item is white waxy solid < 20 °C and a clear colourless liquid at temperatures > 23 °C. The test item may demonstrate some "liquid-crystal" behaviour with an intermediary phase below the melting point where a "waxy" liquid may be observed just below the isotropic phase (molten liquid), based on expert judgement. The test item has not been observed or is not expected to be a liquid at < 20 °C.

 

The test item has been described as a colourless liquid and a white waxy solid under standard conditions of temperature and pressure. The colour of the substance may vary in available sources of various grades of white to colourless. No significant odour has been reported in available sources. The test item has a measured melting/freezing point of 22.6 ± 0.5°C at 97.9 kPa and boiling point of 275.5 ± 2°C at 96.0 kPa in an available melting point and boiling testing to EU Method A.1 and EU Method A.2 under GLP. The test item has also been observed to be a white waxy solid at ambient conditions and a completely molten liquid at > 23 °C in an available Vapour Pressure test to EU Method A.4 study under GLP.

 

The test item under the CLP Regulation (EC) 1272/2008: Annex 1, section 1 concerning the definition of gases, liquids and solids, does not meet the criteria as a gas or liquid. Therefore should be considered as a solid.

For the classification procedure under Regulation (EC) 1272/2008, expert judgment indicates that the intrinsic properties of the test item indicate that the test item would be tested as a solid and/or liquid for specific evaluations. This would be dependent on the respective endpoint, guideline applicability and incorporating expert judgement.

 

References:

1. UN Transport of Dangerous Goods Manual of Tests and Criteria, Sixth Edition (2015)

2. ECHA Guidance on Information Requirements and Chemical Safety Assessment (Chapter R.7a: Endpoint Specific Guidance, July 2017)

3. REACH Regulation (EC) 1907/2006, Annex VII, section 7.1

4. CLP Regulation (EC) 1272/2008, Annex I, section 1

5. ECHA Guidance on Application on the CLP Criteria, section 2.0 (v5.0, July 2017)