Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
17 Nov 2017 to 09 Feb 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Principles of method if other than guideline:
Using a boiling point of 347.10 °C (obtained via computer data search), the vapor pressure was calculated using the Modified Watson Correlation:

Ln(Pvp) = Hvb / (Zb.T.Tb) . [ 1 – {(3-2.Tbp)^m / Tbp} – 2.m. (3 – 2.Tbp.)^(m-1) . ln(Tbp) ]


Pvp = Vapor pressure [atmospheres]
Hvb = Heat of vaporization at the boiling point [cal/mol]
Zb = Compressibility factor (= 0.97)
R = Gas constant [1.987 cal/mol/K]
Tb = Boiling point of the respective substance
Tbp = T/Tb
T = Temperature at which the vapor pressure is to be calculated [K] = 298 K
m = Empirical factor depending on the physical state at T and depending on Tbp (0.19)
Kf = Empirical factor considering the polarity of the test item (1.07)
GLP compliance:
no
Remarks:
The study described in this report was conducted in a facility which operates in accordance with Good Laboratory Practice principles, however no claim of GLP compliance was intended nor is made for this study.
Type of method:
other: Vapor pressure was calculated using the Modified Watson Correlation

Test material

Reference
Name:
Unnamed
Specific details on test material used for the study:
No actual material used, result determined from calculation only.

Results and discussion

Vapour pressure
Key result
Temp.:
25 °C
Vapour pressure:
0.044 Pa

Applicant's summary and conclusion

Conclusions:
The vapor pressure has been calculated to be 4.4 x 10^(-2) Pa at 25 °C.