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EC number: 250-151-3
CAS number: 30364-51-3
The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further toxicity testing with terrestrial organisms.
In accordance with Annex IX, column 2 of Regulation (EC) No
1907/2006, toxicity testing with terrestrial organisms does not need to
be conducted as the Chemical Safety Assessment according to Annex I of
Regulation (EC) No 1907/2006 does not indicate a need for further
Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364-51-3)
has a low adsorption potential due to the low Log Koc of 2.2 – 2.5
(Franco & Trapp, 2008). In addition, the substance is determined to be
readily biodegradable indicating a low potential for persistence. In
addition, the substance has a low potential for bioaccumulation based on
a log Kow of 1.35 (25 °C, Kowwin v1.68) and a log D of 1.52 at the
environmentally relevant pH of 7. This conclusion is supported by the
estimated log BCF values obtained by (Q)SAR, using the BCFBAF model
v3.01, yielding a BCF of 3.16 L/kg wet-wt (regression-based estimate)
and of 1.835 L/kg wet-wt (Arnot-Gobat, including biotransformation,
upper-trophic). Furthermore, the substance is not classified for
environmental hazards according to the Regulation (EC) No 1272/2008
(CLP) and following amendments (ATPs).
All available effect concentrations (EC/LC50) are > 1 mg/L. Thus,
according to Guidance on information requirements and chemical safety
assessment, R.7c (ECHA, 2017) Sodium
N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364-51-3) is in “Hazard
category 1”. Therefore, in accordance with Annex IX, column 2 of
Regulation (EC) No 1907/2006, in the absence of toxicity data for soil
organisms, the equilibrium partitioning method has to be applied to
assess the hazard to soil organisms. The PNEC (soil) was derived with
the Equilibrium Partitioning Method (EPM) for evaluation of the PEC/PNEC
ratio. This screening assessment indicates no risk for the terrestrial
compartment (RCR < 1; please refer to Chapter 9 and 10 of the Chemical
Safety Report for detailed information). Thus, according to Guidance on
information requirements and chemical safety assessment, R.7c (ECHA,
2017), no toxicity testing for terrestrial organisms needs to be done.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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