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Long-term toxicity to aquatic invertebrates

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Endpoint:
long-term toxicity to aquatic invertebrates
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

 The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to aquatic invertebrates.

Key value for chemical safety assessment

Additional information

The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to aquatic invertebrates. Thus, in accordance to Annex VII, column 2 no further long-term toxicity testing to aquatic invertebrates is proposed.

In addition, the environmental exposure assessment for Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364-51-3) indicates no risk for the aquatic compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information).

The substance is not classified for environmental hazards according to the consolidated version of Regulation (EC) No 1272/2008 (CLP) and following amendments (ATPs). Moreover, the substance is determined to be readily biodegradable and according to the Guidance on information requirements and chemical safety assessment, Chapter R.7b, readily biodegradable substances can be expected to undergo rapid and ultimate degradation in most environments, including biological Sewage Treatment Plants (STPs) (ECHA, 2017).

In addition, the substance has a low potential for bioaccumulation based on a log Kow of 1.35 (25 °C, Kowwin v1.68) and a log D of 1.52 at the environmentally relevant pH of 7. This conclusion is supported by the estimated log BCF values obtained by (Q)SAR, using the BCFBAF model v3.01, yielding a BCF of 3.16 L/kg wet-wt (regression-based estimate) and of 1.835 L/kg wet-wt (Arnot-Gobat, including biotransformation, upper-trophic). Thus, the substance is not expected to bioaccumulate in aquatic species.

Therefore, chronic exposure of aquatic organisms is unlikely. Based on the results of the chemical safety assessment and the low bioaccumulation potential no further long-term test with aquatic invertebrates is proposed for Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364-51-3).