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EC number: 250-151-3
CAS number: 30364-51-3
The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
The chemical safety assessment according to Annex I of Regulation
(EC) No 1907/2006 does not indicate the need to investigate further the
long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no
further long-term toxicity testing to fish is proposed.
In addition, the environmental exposure assessment for Sodium
N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364-51-3) indicates no
risk for the aquatic compartment (all RCR < 1; please refer to Chapter 9
and 10 of the Chemical Safety Report for detailed information).
The substance is not classified for environmental hazards
according to the consolidated version of Regulation (EC) No 1272/2008
(CLP) and following amendments (ATPs). Moreover, the substance is
determined to be readily biodegradable and according to the Guidance on
information requirements and chemical safety assessment, Chapter R.7b,
readily biodegradable substances can be expected to undergo rapid and
ultimate degradation in most environments, including biological Sewage
Treatment Plants (STPs) (ECHA, 2017).
In addition, the substance has a low potential for bioaccumulation
based on a log Kow of 1.35 (25 °C, Kowwin v1.68) and a log D of 1.52 at
the environmentally relevant pH of 7. This conclusion is supported by
the estimated log BCF values obtained by (Q)SAR, using the BCFBAF model
v3.01, yielding a BCF of 3.16 L/kg wet-wt (regression-based estimate)
and of 1.835 L/kg wet-wt (Arnot-Gobat, including biotransformation,
upper-trophic). Thus, the substance is not expected to bioaccumulate in
Therefore, chronic exposure of aquatic organisms is unlikely.
Based on the results of the chemical safety assessment and the low
bioaccumulation potential no further long-term test with freshwater fish
is proposed for Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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