Reaction mass of 2-ethylhexyl 12-[(12-hydroxyoctadecanoyl)oxy]octadecanoate and 2-ethylhexyl 12-hydroxyoctadecanoate

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

17 October 2016 to 12 November 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

2-ethylhexyl 12-hydroxyoctadecanoate

EC Number:

249-793-7

EC Name:

2-ethylhexyl 12-hydroxyoctadecanoate

Cas Number:

29710-25-6

Molecular formula:

C26H52O3

IUPAC Name:

2-ethylhexyl 12-hydroxyoctadecanoate

Results and discussion

Water solubility

Water solubility:

< 0 g/L

Conc. based on:

test mat.

Incubation duration:

30 h

Temp.:

20 °C

pH:

> 5.8 - < 6.2

Remarks on result:

other: Less than 1.07 x 10^-5 g/L at 20.0 ± 0.5 °C

Details on results:

The Preliminary test: The preliminary estimate of water solubility at 20.0 ± 0.5 °C was less than 1.06 x 10-4 g/L. The solution had a pH of 6.1.

Definitive Test: The mean peak areas relating to the standard and sample solutions are shown in the following tables:
Solution = Mean Peak Area:
Standard 0.011 mg/L = 6.023 x 105
Standard 0.054 mg/L = 2.410 x 106
Standard 0.107 mg/L = 5.196 x 106
*Standard 0.529 mg/L = 3.848 x 107
Standard 0.537 mg/L = 1.859 x 107
Standard 1.07 mg/L = 3.546 x 107
Standard 2.68 mg/L = 7.131 x 107
Standard 5.37 mg/L = 1.128 x 108
Blank = none detected
Sample 1A = 3.1161 x 104
Sample 1B = 1.7466 x 104
Sample 2A = 1.6035 x 104
Sample 2B = 4.0564 x 103
Sample 3A = 1.6288 x 104
Sample 3B = 1.6321 x 104

Any other information on results incl. tables

Definitive Test

The concentration (g/L) of test item in the sample solutions at 20.0 ± 0.5 ºC are shown in the following table:

Sample Number	Time Shaken at ~ 30 ºC (hours)	Concentration (g/L)	Solution pH
1	24	<1.07 x 10-5	6.2
2	48	<1.07 x 10-5	5.8
3	72	<1.07 x 10-5	5.8

Applicant's summary and conclusion

Conclusions:

The water solubility of the test item has been determined to be less than 1.07 x 10^-5 g/L of solution at 20.0 ± 0.5 °C.

Executive summary:

The water solubility was less than 1.07 x 10^-5 g/L at 20.0 ± 0.5 °C using the flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.