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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Test organisms (species):
Oryzias latipes
Details on test organisms:
This species is similar in sensitivity to carp and readily available as test fish.
Test type:
semi-static
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Validity criteria fulfilled:
yes
Conclusions:
The test item was a mixture of the reaction products (1-(3-(Dimethylamino)propyl)urea (CAS 31506-43-1, EC 401-950-2, monoDMAPAU) )and 1,3-bis[3-(dimethylamino)propyl]urea (CAS 52338-87-1, EC 257-861-2, bisDMAPAU)
The 96-hour LC50 for orange red killifish (Oryzias latipes))exposed to DMPA Urea was >1000 mg/l

Description of key information

The test item was a mixture of the reaction products (1-(3-(Dimethylamino)propyl)urea (CAS 31506-43-1, EC 401-950-2, monoDMAPAU) )and 1,3-bis[3-(dimethylamino)propyl]urea (CAS  52338-87-1, EC 257-861-2, bisDMAPAU).

The 96-hour LC50 for orange red killifish (Oryzias latipes))exposed to DMPA Urea was >1000 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information

The 96-hour LC50 for orange red killifish (Oryzias latipes) exposed to DMAPA Urea was > 1000 mg/l