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EC number: 257-861-2 | CAS number: 52338-87-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Test organisms (species):
- Oryzias latipes
- Details on test organisms:
- This species is similar in sensitivity to carp and readily available as test fish.
- Test type:
- semi-static
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test item was a mixture of the reaction products (1-(3-(Dimethylamino)propyl)urea (CAS 31506-43-1, EC 401-950-2, monoDMAPAU) )and 1,3-bis[3-(dimethylamino)propyl]urea (CAS 52338-87-1, EC 257-861-2, bisDMAPAU)
The 96-hour LC50 for orange red killifish (Oryzias latipes))exposed to DMPA Urea was >1000 mg/l
Reference
Description of key information
The test item was a mixture of the reaction products (1-(3-(Dimethylamino)propyl)urea (CAS 31506-43-1, EC 401-950-2, monoDMAPAU) )and 1,3-bis[3-(dimethylamino)propyl]urea (CAS 52338-87-1, EC 257-861-2, bisDMAPAU).
The 96-hour LC50 for orange red killifish (Oryzias latipes))exposed to DMPA Urea was >1000 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
The 96-hour LC50 for orange red killifish (Oryzias latipes) exposed to DMAPA Urea was > 1000 mg/l
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