Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Type:
- Koc
- Remarks:
- peak 1
- Value:
- ca. 40 849 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Key result
- Type:
- log Koc
- Remarks:
- peak 1
- Value:
- ca. 4.6 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Key result
- Type:
- Koc
- Remarks:
- peak 2
- Value:
- ca. 94 426 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Key result
- Type:
- log Koc
- Remarks:
- peak 2
- Value:
- ca. 5 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Key result
- Type:
- Koc
- Remarks:
- peak 3
- Value:
- ca. 444 823 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Key result
- Type:
- log Koc
- Remarks:
- peak 3
- Value:
- ca. 5.6 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: Other details are not available
- Validity criteria fulfilled:
- yes
- Conclusions:
- FAT 41048 can be considered immobile and to remain preferably in soil.
- Executive summary:
The determination of the adsorption coefficient (Koc) of FAT 41039/A, structural analogue of FAT 41048, was performed according to the OECD Guideline for the Testing of Chemicals, No. 121, Estimation of the Adsorption Coefficient (Koc) on Soil and Sewage Sludge using High Performance Liquid Chromatography (HPLC), January, 2001 and the EC Directive 2001/59, C.19.
The test item solution was injected three times and the combined reference solution was injected six times. The log Koc for each peak of the test item was calculated using a regression curve (log k' vs. log Koc) and was found to be 4.6, 5.0 and 5.6 respectively, which is equal to a Koc value of 40849, 94426 and 444823, respectively. In the present study the reference items covered the range of log Koc 1.25 to log Koc 5.63. The chromatography of the test item resulted in three main peaks that could not be separated very well from each other. The retention time of each peak was reproducible.
The HPLC method was therefore considered to be suitable for the purpose of the study.
Based on the chromatographic data, FAT 41039/A was considered to be stable during the test procedure. The peak at about 2.5 minutes was due to the solvent (this peak could also be detected in the HPLC-chromatogram of the blank solution).
In conclusion, the log of the adsorption coefficient (Koc) of FAT 41039/A was estimated to be
1st Peak log Koc = 4.6 which is equal to a Koc value of 40849
2nd Peak log Koc = 5.0 which is equal to a Koc value of 94426
3rd Peak log Koc = 5.6 which is equal to a Koc value of 444823
using the HPLC method. These values indicate that FAT 41039/A is immobile and remains preferably in soil. Using principles of read across, FAT 41048 can also be considered to be immobile and to remain in soil.
Reference
The log Koc for each peak of the test item was calculated using a regression curve (log k' vs. log Koc) and was found to be 4.6, 5.0 and 5.6 respectively, which is equal to a Koc value of 40849, 94426 and 444823, respectively. In the present study the reference items covered the range of log Koc 1.25 to log Koc 5.63.
The chromatography of the test item resulted in three main peaks that could not be separated very well from each other. The retention time of each peak was reproducible. The HPLC method was therefore considered to be suitable for the purpose of the study. Based on the chromatographic data, FAT 41039/A was considered to be stable during the test procedure. The peak at about 2.5 minutes was due to the solvent (this peak could also be detected in the HPLC-chromatogram of the blank solution).
Description of key information
FAT 41048 can be considered immobile and to remain preferably in soil.
Key value for chemical safety assessment
- Koc at 20 °C:
- 40 849
Additional information
The determination of the adsorption coefficient (Koc) of FAT 41039/A, structural analogue of FAT 41048, was performed according to the OECD Guideline for the Testing of Chemicals, No. 121, Estimation of the Adsorption Coefficient (Koc) on Soil and Sewage Sludge using High Performance Liquid Chromatography (HPLC), January, 2001 and the EC Directive 2001/59, C.19.
The test item solution was injected three times and the combined reference solution was injected six times. The log Koc for each peak of the test item was calculated using a regression curve (log k' vs. log Koc) and was found to be 4.6, 5.0 and 5.6 respectively, which is equal to a Koc value of 40849, 94426 and 444823, respectively. In the present study the reference items covered the range of log Koc 1.25 to log Koc 5.63. The chromatography of the test item resulted in three main peaks that could not be separated very well from each other. The retention time of each peak was reproducible.
The HPLC method was therefore considered to be suitable for the purpose of the study.
Based on the chromatographic data, FAT 41039/A was considered to be stable during the test procedure. The peak at about 2.5 minutes was due to the solvent (this peak could also be detected in the HPLC-chromatogram of the blank solution).
In conclusion, the log of the adsorption coefficient (Koc) of FAT 41039/A was estimated to be
1st Peak log Koc = 4.6 which is equal to a Koc value of 40849
2nd Peak log Koc = 5.0 which is equal to a Koc value of 94426
3rd Peak log Koc = 5.6 which is equal to a Koc value of 444823
using the HPLC method. These values indicate that FAT 41039/A is immobile and remains preferably in soil. Using principles of read across, FAT 41048 can also be considered to be immobile and to remain in soil.
[LogKoc: 4.6]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
