Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
Batch identification: 21747297VO
Storage condtions: ambient temperature, moisture proofing

Results and discussion

Melting / freezing point
Key result
Remarks on result:
not determinable
Remarks:
The test item had no melting temperature between O °C and decomposition of the test item starting at about 220 °C.

Any other information on results incl. tables

Results in detail

No melting temperature was found between O °C and decomposition of the test item, starting at about 220 °C.

The estimated accuracy is ± 1 °C.

Observed thermal processes

Starting at about 50 °C up to about 180 °C, an endothermal area was observed at all determinations. After determination Test 2 (up to 180 °C) the test item was as powdery as before and the color

changed slightly darker. This was a clear indication that the observed endothermic area and the registered weight loss of 3.2 % showed mainly the vaporization of volatiles, but a beginning degradation

cannot be excluded.

Another endothermal peak at 203 °C peak temperature was found in Test 1 and 3. After determination Test 1 (up to 250 °C) the test item was as powdery as before and the color changed into a dark

brown. Therefore, the test item was not molten up to this temperature. The distinct weight loss after this measurement (8.7 %) and the continuously increasing weight loss in the TG/DSC-measurement

(non-GLP) clearly suggest that already the endothermic maximum around 200 °C is caused by a beginning degradation.

After determination Test 3 (up to 360 °C) the test item was still powdery as before but the color changed into black. Therefore, no melting occurred up to this end temperature. However, latest with the

beginning of the exothermic regime at about 220 °C (Test 1 and 3), a degradation of the test item is ensured.

These observations are confirmed by the preliminary TG/DSC-Test (non-GLP). A stepwise weight loss starting at about 150 °C with a weight loss of about 17 % at 600 °C showed the decomposition of

the test item.

Applicant's summary and conclusion