Registration Dossier
Registration Dossier
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EC number: 446-640-8 | CAS number: -
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes
Test material
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
- Transformation products:
- not measured
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- > 8 760 h
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- > 8 760 h
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- According to the EEC Directive 92/69, Section C.7 it can be concluded, that the estimated
half-life time is higher than one year under representative environmental conditions (25”C).
Therefore, ucb 22060 was considered to be hydrolytically stable, and no further testing was
necessary. - Executive summary:
The hydrolysis determination of ucb 22060 at different pH values was based on the OECD Guideline No. 111, “Hydrolysis as a Function of pH”; adopted May 12, 1981 and on the EEC Directive 92/69, Section C.7, “Abiotic Degradation: Hydrolysis as a Function of pH”, L383 A, December 1992. The results of pH 4.0, pH 7.0 and pH 9.0 showed no significant degradation of ucb 22060 at 50°C. The degradation of ucb 22060 was less than 10 % after 5 days. The results are summarised in the table abov. pH Hydrolysis after 5 days, 50°C [%] 4.0
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