Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
29 January 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on QSAR predictions supported by reliable experimental data on an analogous substance

Data source

Reference
Reference Type:
other: expert assessment
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Assessment based on QSAR predictions supported by reliable experimental data on an analogous substance
Type of study:
other: Assessment based on QSAR predictions supported by reliable experimental data on an analogous substance

Test material

Constituent 1
Chemical structure
Reference substance name:
trans-hex-2-en-1-ol
EC Number:
213-191-2
EC Name:
trans-hex-2-en-1-ol
Cas Number:
928-95-0
Molecular formula:
C6H12O
IUPAC Name:
hex-2-en-1-ol

Results and discussion

In vivo (non-LLNA)

Results
Key result
Remarks on result:
other: Trans-hex-2-en-1-ol is not expected to induce skin sensitisation

Any other information on results incl. tables

see attached report

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Trans-hex-2-en-1-ol is not expected to induce skin sensitisation.
Executive summary:

Assessment based on QSAR predictions supported by reliable experimental data on an analogous substance. It concluded that Trans-hex-2-en-1-ol is not expected to induce skin sensitisation.