Registration Dossier
Registration Dossier
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EC number: 213-191-2 | CAS number: 928-95-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- TEST ORGANISM
- Common name: Pseudokirchneriella subcapitata
- Strain: 278/4
- Source (laboratory, culture collection): SAMS Limited
- Age of inoculum (at test initiation):
- Method of cultivation: culture were prepared from stock laboratory cultures by inoculating autoclaved freshwater at 120 °C for 15 minutes with nutrient medium (3N-BBM+V) 2 to 4 days before test commencement and incubated at approximately 21 +/- 2 °C under constant illumination as the inoculum source for subsequent toxicity tests.
ACCLIMATION
- Culturing media and conditions: same as test
- Any deformed or abnormal cells observed: None reported - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 226 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N°1272/2008.
- Executive summary:
The short-term toxicity of Trans-hex-2-en-1-ol to algae was determined during a GLP-compliant study performed according to the OECD Testing Guideline 201.
The species was Pseudokirchneriella subcapitata.
A range-finding test was performed to determine the concentrations to be used during the definitive test.
The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N° 1272/2008.
Reference
Description of key information
The short-term toxicity of Trans-hex-2-en-1-ol to algae was determined during a GLP-compliant study performed according to the OECD Testing Guideline 201.
The species was Pseudokirchneriella subcapitata.
A range-finding test was performed to determine the concentrations to be used during the definitive test.
The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N° 1272/2008.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 226 mg/L
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