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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Details on test organisms:
TEST ORGANISM
- Common name: Pseudokirchneriella subcapitata
- Strain: 278/4
- Source (laboratory, culture collection): SAMS Limited
- Age of inoculum (at test initiation):
- Method of cultivation: culture were prepared from stock laboratory cultures by inoculating autoclaved freshwater at 120 °C for 15 minutes with nutrient medium (3N-BBM+V) 2 to 4 days before test commencement and incubated at approximately 21 +/- 2 °C under constant illumination as the inoculum source for subsequent toxicity tests.

ACCLIMATION
- Culturing media and conditions: same as test
- Any deformed or abnormal cells observed: None reported
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
226 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Validity criteria fulfilled:
yes
Conclusions:
The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N°1272/2008.
Executive summary:

The short-term toxicity of Trans-hex-2-en-1-ol to algae was determined during a GLP-compliant study performed according to the OECD Testing Guideline 201.

The species was Pseudokirchneriella subcapitata.

A range-finding test was performed to determine the concentrations to be used during the definitive test.

The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N° 1272/2008.

Description of key information

The short-term toxicity of Trans-hex-2-en-1-ol to algae was determined during a GLP-compliant study performed according to the OECD Testing Guideline 201.

The species was Pseudokirchneriella subcapitata.

A range-finding test was performed to determine the concentrations to be used during the definitive test.

The 72-hour EC50 was 226 mg/L. The substance did not meet the criteria for classification as toxic to the aquatic environment according to Regulation (EC) N° 1272/2008.

Key value for chemical safety assessment

EC50 for freshwater algae:
226 mg/L

Additional information