Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-429-8 | CAS number: 159034-96-5
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the physicochemical properties of the substance indicate that it can be expected to have a low potential for adsorption
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
No testing of the adsorption coefficient could be performed using the HPLC screening method for the following reasons, designed to be compatible with Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001 and Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008.
• The test item was found to be insoluble in most organic solvents including typical reverse phase and normal phase solvents.
• The test item was soluble in 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) at a level of 1 g/L. Analysis of the solution was attempted by reverse phase chromatography using a C18 column with gradient mobile phase using acetonitrile and water. No reliable chromatography was achieved.
Reference
Description of key information
The study does not need to be conducted because the physicochemical properties of the substance indicate that it can be expected to have a low potential for adsorption:
HPLC screening method was not applicable due to the low solubility of the test item in reverse phase solvents. In addition, the water solubility of the test item (as total dissolved carbon) was also low ( in the range of <1E-3 g/L to 1.16 E-2 g/L at 20.0 ± 0.5 °C).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
