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EC number: 205-271-0 | CAS number: 136-99-2
Under the conditions described above, the following lethality rates were observed:
The acute oral toxicity testing of Lauryl-hydroxyethylimidazolinei n the rat yielded the following median lethal dose (LD50): Female animals: 448.9 mg/kg body weight Male animals did not show a higher sensitivity to the test substance. Lethality occurred up to day two of the study. Besides unspecific symptoms the animals showed impairments of motility and respiration as well as drawn in flanks. Additionally, hypoactivity, stupor, bristling coat, narrow palpebral fissures and trembling and were observed. Development of body weight was not impaired. Necropsy of the decedent animals revealed black discolored spleen, stomach filled with gas, diffuse reddening of the stomach mucosa and detachment of the stomach and small intestine mucosa as well as blood in the small intestine, small intestine filled with dark yellow mucous, urine bladder filled with dark red fluid, positive test of blood in urine, abdominal cavity filled with light red fluid. The animals killed at the end of the observation period showed no macroscopically visible changes.
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