Registration Dossier
Registration Dossier
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EC number: 614-114-9 | CAS number: 67746-08-1
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 February 2010 – 17 March 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- in accordance with GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: estimation method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Linseed oil, polymerized
- EC Number:
- 614-114-9
- Cas Number:
- 67746-08-1
- Molecular formula:
- Not applicable for UVCB
- IUPAC Name:
- Linseed oil, polymerized
- Details on test material:
- - Name of test material (as cited in study report): Standolized linseed oil
- Substance type: Hazy yellow/brown viscous liquid
- Physical state: liquid
- Analytical purity: treated as 100% pure
- Lot/batch No.: 09.317.013
- Expiration date of the lot/batch: 21 December 2010
- Stability under test conditions: stable
- Storage condition of test material: At room temperature in the dark
- Other: -
1
Study design
- Analytical method:
- other: see details on method
Results and discussion
Partition coefficientopen allclose all
- Key result
- Type:
- Pow
- Partition coefficient:
- > 1 000 000
- Temp.:
- 20 °C
- pH:
- 6.8
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 6
- Temp.:
- 20 °C
- pH:
- 6.8
- Details on results:
- n-Octanol solubility
After stirring for 50 hours, the test solution with a nominal concentration of 1059 g/L was a clear solution without undissolved test substance. Based on this, it was concluded that the solubility of Standolized linseed oil in n-octabol at 19.9 +/- 0.8°C is > 1000 g/l.
Water solubility
Information on the water solubility of the test substance is given in section 4.8. The water solubility was < 1 x 10-3 g/l.
Applicant's summary and conclusion
- Conclusions:
- Partition coefficient
The estimation method was used for the determination of the Pow of Standolized linseed oil. The Pow and log Pow value of the test substance at 20°C was calculated from the n-octanol solubility and the water solubility to be > 1 x 10^6 and > 6.
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