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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Remarks:
Solubility in n-Octanol
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: OECD Guideline 105 (Water Solubility)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction mass of N-(3-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}propyl)-N,N-dimethyldocosan-1-aminium chloride and N-(3-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}propyl)-N,N-dimethylicosan-1-aminium chloride
EC Number:
947-079-6
IUPAC Name:
Reaction mass of N-(3-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}propyl)-N,N-dimethyldocosan-1-aminium chloride and N-(3-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}propyl)-N,N-dimethylicosan-1-aminium chloride
Test material form:
other: paste
Specific details on test material used for the study:
Product identification: GalHueShield HCS
Batch: GHS-HCS#08
Appearance: Off white pasty solid
Solids, % by mass: 30.38

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
n-octanol
Solubility:
0.014 other: kg/kg (expressed as mass of solute per mass of solution)
Temp.:
25 °C
Test substance stable:
not determined

Any other information on results incl. tables

Experimental data:

No

Period (equilibration time)

Temperature

Solubility

 

(h)

(°C)

(kg/m3)

1

24

25

10.944

2

48

25

11.356

3

72

25

11.433

Average

11.24 kg/m3

 

Density of n-Octanol at 25°C is 827 kg/m3

So the solubility is:

Solubility (in kg/kg): 11.43 kg/m3 / 827 kg/m3 = 1.38 x 10-2 kg/kg

Applicant's summary and conclusion

Conclusions:
The solubility of GalHueShield HCS in n-octanol is 1.38 x 10-2 at 25°C (expressed as mass of solute per mass of solution).
Executive summary:

The solubility of GalHueShield HCS was determined as per OECD Guideline No. 105 (flask method).

The solubility of GalHueShield HCS in n-octanol is 1.38 x 10-2 at 25°C (expressed as mass of solute per mass of solution).