Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23 May 2016 - 02 May 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
Appearance: off-white powder
Test item storage: at room temperature
Specific details on test material used for the study:
Decomposition temp.: 300°C
Melting temp.: 182.8°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature [°C]

Weight loss [µg/min]

νT

[g/cm2/h]

log νT

log PT

PT[Pa]

 

140

 

2.66516

 

3.18×10-4

 

-3.50

 

0.27

 

1.8

 

 

3.10305

 

3.70×10-4

 

-3.43

 

0.35

 

2.3

 

150

5.82071

6.95×10-4

-3.16

0.72

5.3

 

 

5.46058

 

6.52×10-4

 

-3.19

 

0.68

 

4.8

 

160

10.6758

1.27×10-3

-2.89

1.07

12

 

 

12.0525

 

1.44×10-3

 

-2.84

 

1.15

 

14

 

170

23.2710

2.78×10-3

-2.56

1.53

34

 

 

22.0036

 

2.63×10-3

 

-2.58

 

1.50

 

31

 

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C was determined to be 1.0E-7 Pa.
The vapour pressure of the substance at 25°C was determined to be 2.7E-7 Pa.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. A vapour pressure curve for the test item was constructed from duplicate measurements at 140°C, 150°C, 160°C and 170°C. The vapour pressure of the substance at 20°C and 25°C was determined by extrapolation to be 1.0E-7 Pa and 2.7E-7 Pa, resp.