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Environmental fate & pathways

Hydrolysis

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Description of key information

Two studies are available investigating the hydrolysis of two different read across substances. A reliable Klimisch 2 (OECD Guideline, to GLP standards) study assessed hydrolysis of the read across substance, Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates (CAS number 931 -745 -8), based on the C18:1/C18:1 imidazolinium quat constituent. The half-life (lives)/DT50 (50% decline times) of the test item were determined at > 1 year at 25°C at pH 4 and as 2.9 days at 20°C, 2.5 days at 25°C, 27 hours at 50°C and 16 hours at 60°C (all at pH 7). The other study is for the read across substance fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (CAS number 937 -237 -2), however the hydrolysis of this substance was not able to be assessed due to the substance being insoluble.

In conclusion (based on a weight of evidence approach) from the data on the read across substances it is evident that some of the constituents of the test substance are likely to undergo hydrolysis, however this may not be an important process for other constituents that are largely insoluble, at least at the concentrations required in hydrolysis tests.

Key value for chemical safety assessment

Half-life for hydrolysis:
2.9 d
at the temperature of:
20 °C

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