Registration Dossier
Registration Dossier
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EC number: 256-589-1 | CAS number: 50448-95-8
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- short-term repeated dose toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- A study according to OECD TG 422 is commissioned and will be finished in Q4 2022. Results will be reported as soon as available
Data source
Reference
- Title:
- Unnamed
- Year:
- 2 022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-ethylhexyl 3-mercaptopropionate
- EC Number:
- 256-589-1
- EC Name:
- 2-ethylhexyl 3-mercaptopropionate
- Cas Number:
- 50448-95-8
- Molecular formula:
- C11H22O2S
- IUPAC Name:
- 2-ethylhexyl 3-sulfanylpropanoate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
Administration / exposure
- Route of administration:
- oral: gavage
- Control animals:
- yes, concurrent vehicle
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- 0 mg/kg bw/day (actual dose received)
- Sex:
- male/female
- Basis for effect level:
- other:
- Remarks on result:
- other: results will be reported as soon as the study is finalized
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
