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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
Please refer to the attached justification below and the overall justification for grouping of substances attached in IUCLID Section 13.
Reason / purpose:
read-across source
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
74 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: 95% C.I.: 53 to 103 mg/L
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
10 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Details on results:
- Mortality of control: 0%

Description of key information

EC50 (48 h) = 74 mg/L (nominal, OECD 202) based on read across from reaction mass containing six benzylated amine silanes (EC 700-961-2).

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
74 mg/L

Additional information

Experimental data on the acute toxicity of 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate,hydrochlorides (CAS 171869-89-9) towards aquatic invertebrates are not available. Therefore, in accordance with the Regulation (EC) No. 1907/2006 Annex XI, 1.5 “Grouping of substances and read across” and the read across assessment framework (RAAF, ECHA 2017) a read across from the analogue substance reaction mass containing six benzylated amine silanes (EC 700-961-2) has been performed. Details on the read-across justification can be found in the attached justification in the respective target entry and in the overall justification for grouping of substances attached in IUCLID Section 13.

One study is available testing the short term toxicity of reaction mass containing six benzylated amine silanes (EC 700-961-2) to aquatic invertebrates. The study was conducted with Daphnia magna as the test organism and according to the OECD guidance 202. The EC50 (48 h) was determined to be 74 mg/L (nominal). Since the tested substance hydrolysis easily in water it is very likely that test organisms were primarily exposed to the hydrolysis products of the substance.

Acute toxicity effects were observed for the analogue substance and as explained in the attached read across justification (see IUCLID target entry) similar results are expected from 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-, N-{(ethenylphenyl)methyl}derivate, hydrochlorides (CAS 171869-89-9).