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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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short-term toxicity to aquatic invertebrates
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is highly insoluble in water, hence indicating that aquatic toxicity is unlikely to occur
Justification for type of information:
A QSAR evaluation was carried out for the substance, to assess its potential for toxicity to fish. The logKow value of 6.13, which is itself a QSAR result, was used as input. The value for water solubility used in the assessment was 0.3 mg/l. The logKow of the substance is 6.13, which is above the cut-off value of 5.0, for the neutral substance, which, according to the model, means that no effects are expected at saturation for this endpoint. The limit of water solubility (0.3 mg/L) is taken as the EC50 for PNEC derivation.
Reason / purpose:
data waiving: supporting information

Description of key information

The study does not need to be conducted, because the substance is highly insoluble in water. The limit of solubility of the substance in water is listed below.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
0.3 mg/L
EC50/LC50 for marine water invertebrates:
0.3 mg/L

Additional information