Registration Dossier
Registration Dossier
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EC number: 200-852-5 | CAS number: 75-23-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 979
- Report date:
- 1979
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- orientation test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ethylamine-boron trifluoride
- EC Number:
- 200-852-5
- EC Name:
- Ethylamine-boron trifluoride
- Cas Number:
- 75-23-0
- Molecular formula:
- C2H7BF3N
- IUPAC Name:
- ethanamine; trifluoroborane
Constituent 1
- Specific details on test material used for the study:
- not specified
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- not specified
- Amount / concentration applied:
- not specified
- Duration of treatment / exposure:
- not specified
- Observation period (in vivo):
- not specified
- Duration of post- treatment incubation (in vitro):
- not specified
- Number of animals or in vitro replicates:
- not specified
- Details on study design:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- other: not specified
- Basis:
- other: not specified
- Time point:
- other: not specified
- Score:
- >= 1.4
- Max. score:
- 1.4
- Reversibility:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritating to eyes) based on GHS criteria
- Conclusions:
- the test report concludes only minimal eye irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as eye irritant
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