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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethylamine--boron trifluoride
EC Number:
200-852-5
EC Name:
Ethylamine--boron trifluoride
Cas Number:
75-23-0
Molecular formula:
C2H7BF3N
IUPAC Name:
ethylamine--boron trifluoride
Specific details on test material used for the study:
not specified

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period (in vivo):
not specified
Duration of post- treatment incubation (in vitro):
not specified
Number of animals or in vitro replicates:
not specified
Details on study design:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.4
Max. score:
1.4
Reversibility:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritating to eyes) based on GHS criteria
Conclusions:
the test report concludes only minimal eye irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as eye irritant

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