Registration Dossier

Administrative data

Description of key information

ethylamine--boron trifluoride is known to cause irritation of skin, eyes and the respiratory trackt

Key value for chemical safety assessment

Skin irritation / corrosion

Link to relevant study records
Reference
Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified
Species:
rabbit
Strain:
not specified
Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period:
not specified
Number of animals:
not specified
Details on study design:
not specified
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.75
Max. score:
1.75
Reversibility:
not specified
Remarks on result:
probability of weak irritation
Interpretation of results:
Category 2 (irritant) based on GHS criteria
Conclusions:
the test report concludes only slight skin irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as skin irritant irritant
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified
Specific details on test material used for the study:
not specified
Species:
rabbit
Strain:
not specified
Vehicle:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period (in vivo):
not specified
Duration of post- treatment incubation (in vitro):
not specified
Number of animals or in vitro replicates:
not specified
Details on study design:
not specified
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.4
Max. score:
1.4
Reversibility:
not specified
Interpretation of results:
Category 2 (irritating to eyes) based on GHS criteria
Conclusions:
the test report concludes only minimal eye irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as eye irritant
Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Justification for classification or non-classification