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EC number: 701-230-0 | CAS number: -
A group of 6 fasted animals (3 males and 3 females) was given a single oral dose of test material preparation in aqua bidest at the dose level of 200 mg/kg bw. Another group of 3 females was treated in the same way with a dose of 2000 mg/kg bw.
The animals treated with 200 mg/kg bw did not show any mortality or symptoms. No abnormalities were noted at necropsy of animals sacrificed at the end of the study.
Signs of toxicity noted in females treated with 2000 mg/kg bw comprised poor general state, dyspnea, apathy, abdominal position, atonia, paresis, cyanosis and diarrhea. All females treated with 2000 mg/kg bw died 4 hours or 1 day after treatment. Necropsy findings of the animals that died was general congestion.
Under the conditions of this study, the range of LD50 after oral application was found to be greater than 200 mg/kg bw and less than 2000 mg/kg bw.
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