Registration Dossier

Diss Factsheets

Ecotoxicological information

Endpoint summary

Currently viewing:

Administrative data

Description of key information

Additional information

This aquatic toxicity assessment was based on the following data:


 


The short-term toxicity of the test substance to fish was investigated in a GLP guideline study according to OECD 203. The LC50 (96h) on Danio rerio was determined to be 66.8 mg/L, based on analytically verified nominal concentrations.


 


The toxicity of the test substance to aquatic invertebrates was investigated in a GLP guideline study according to OECD 202. The EC50 (48h) on Daphnia magna was determined to exceed the only tested, analytically verified nominal test concentration of 100 mg/L (limit test).


 


The toxicity of the test substance to aquatic algae was investigated in a GLP guideline study according to OECD 201. The ErC50 (72h) on Pseudokirchneriella subcapitata was determined to be 61.6 mg/L, based on analytically verified nominal concentrations. The ErC10 (72h) was determined to be 22.5 mg/L, based on analytically verified nominal concentrations.


 


The toxicity of the test substance to microorganisms was investigated by the conduction of an inhibition control in the framework of a ready biodegradability study (OECD 301 F). The domestic, non-adapted activated sludge used as inoculum showed no significant inhibition of its degradation potential after a test duration of 28 days at a test substance concentration of 100 mg/L. This result is supported by the outcome of a guideline study similar to OECD 209, for which only a summary is available. In this study, an EC50 (30 min) > 100 mg/L was determined. Based on these results, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.