Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 288-492-5 | CAS number: 85736-79-4
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19.7.1991-30.7.1991
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Soviet union (Estonia) national standards
- Version / remarks:
- Year 1990 national standards, approved by Health ministry.
- GLP compliance:
- not specified
- Type of study:
- other: According to National standard of Estonia (Soviot Union) 1990
- Justification for non-LLNA method:
- Method according to national standars, from year 1990 according to best test methods of that time.
Test material
- Reference substance name:
- Sulfonic acids, C13-17-sec-alkane, compds. with triethanolamine
- EC Number:
- 288-492-5
- EC Name:
- Sulfonic acids, C13-17-sec-alkane, compds. with triethanolamine
- Cas Number:
- 85736-79-4
- Molecular formula:
- Sulfonic acid, C13-17-sec-alkane: C13H28O3S (MW 264,42) - C17H36O3S (MW 320,53) and 2,2',2''-nitrilotriethan: C6H15NO3 (MW 149,19) , typical medium molecular weight of mixture 454 g/mol.
- IUPAC Name:
- Sulfonic acids, C13-17-sec-alkane, compds. with triethanolamine
- Test material form:
- liquid: viscous
Constituent 1
- Specific details on test material used for the study:
- Fain, 1990
In vivo test system
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals and environmental conditions:
- 500 g weight animals.
Study design: in vivo (non-LLNA)
Induction
- Route:
- epicutaneous, open
- Vehicle:
- unchanged (no vehicle)
- Concentration / amount:
- 2.5 g/kg, 2 g/kg, 0.6 g/kg
- Day(s)/duration:
- Not specified
- Adequacy of induction:
- not specified
Challenge
- No.:
- #1
- Route:
- epicutaneous, open
- Vehicle:
- unchanged (no vehicle)
- Concentration / amount:
- 2,5 g/kg
- Day(s)/duration:
- Not specified
- Adequacy of challenge:
- not specified
- No. of animals per dose:
- 50
- Details on study design:
- The sample was used at the amounts of 2,5 g, 1,2 g and 0,6 g / weight kilogram.
- Challenge controls:
- As a reference, a Krja-Krja-shampoo and Physiologial solution was tested.
- Positive control substance(s):
- not specified
- Remarks:
- according to national standards
Results and discussion
- Positive control results:
- Not specified, according to national standards. Full information not available in English/Finnish.
In vivo (non-LLNA)
Resultsopen allclose all
- Key result
- Reading:
- other: not specified
- Group:
- test chemical
- Dose level:
- 2,5 g/Kg maximum
- No. with + reactions:
- 0
- Total no. in group:
- 50
- Remarks on result:
- no indication of skin sensitisation
- Key result
- Reading:
- other: not specified
- Group:
- negative control
- Dose level:
- 2,5 g/kg maximum
- No. with + reactions:
- 0
- Total no. in group:
- 50
- Remarks on result:
- no indication of skin sensitisation
- Key result
- Reading:
- other: not specified
- Group:
- positive control
- Dose level:
- 0
- No. with + reactions:
- 0
- Total no. in group:
- 0
- Clinical observations:
- information not available
- Remarks on result:
- other: information not available
Any other information on results incl. tables
Only Certificate and Summary available in Finnish language, none in english. Therefore all information is not complete here.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Although all information is not available to us, the results are clear and based on the national standards and made by relialable laboratory, confirmed by authoroties. As a conclusion, Fain did not cause skin sensitisation.
- Executive summary:
Fain did not cause skin sensitisation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
