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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 Mar 2018 to 03 May 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Version / remarks:
March 04, 2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Version / remarks:
January 22, 2001
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: EC Technical Guidance Document on Risk Assessment Part III Chapter 4.3: Use of (Quantitative) Structure Activity Relationships ((Q)SARs) - Soil and Sediment Sorption.
Version / remarks:
2003
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC estimation method
Specific details on test material used for the study:
Appearance: Clear to transparent yellow liquid
Purity/Composition: Not indicated
Test item storage: At room temperature
Test temperature:
20 °C
Details on study design: HPLC method:
Analytical Conditions

Instrument: Acquity UPLC system (Waters, Milford, MA, USA)
Detector: Acquity UPLC PDA detector (Waters)
Detector: Xevo TQ-S mass spectrometer (Waters)
Column: Acquity UPLC HSS Cyano, 100 mm x 2.1 mm i.d., dp = 1.8 µm (Waters)
Column temperature: 35 ± 1°C
Injection volume: 5 µL
Mobile phase: 55/45 (v/v) methanol/buffer pH 4
Flow: 0.4 mL/min
UV detection: 210 nm
MS detection:
- Ionization source: ESI+
- Cone voltage: 40 V
- Quantitation: m/z 221
MS detection
- Ionization source: ESI-
- Cone voltage: 40 V
- Quantitation: m/z 115
Key result
Type:
log Koc
Value:
< 1.26 dimensionless
pH:
4
Validity criteria fulfilled:
yes
Conclusions:
The adsorption coefficient (Koc) of the test material has been determined to be log Koc: < 1.26.
Executive summary:

The adsorption coefficient (Koc) of the test material has been determined in accordance to the standardised guideline OECD 121, under GLP conditions log Koc: < 1.26.

Description of key information

The adsorption coefficient (Koc) of the test material has been determined in accordance to the standardised guideline OECD 121, under GLP conditions log Koc: < 1.26.

Key value for chemical safety assessment

Koc at 20 °C:
1.26

Additional information