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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20 February 2018 to 10 September 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Identification:
- Bis-Aminopropyl Diglycol Dimaleate
- Appearance: Clear to transparent yellow liquid
- Purity/Composition: Not indicated
- Test item storage: At room temperature

Additional information
- Test Facility test item number: 207396/C
- Purity/Composition correction factor: Contains 74% water
- Test item handling: No specific handling conditions required
- Stability at higher temperatures: Yes, maximum temperature: 40°C, maximum duration: 60 minutes
- EC number: 818-033-1
- Molecular formula: C18H32N2O11
- Molecular weight: 452.46
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
-2.8
Temp.:
20 °C
pH:
4.3
Remarks on result:
other:
Remarks:
Cation Log Pow of <-2.8
Key result
Type:
log Pow
Partition coefficient:
-2.4
Temp.:
20 °C
pH:
4.3
Remarks on result:
other:
Remarks:
Anion
Details on results:
CATION:
Partition coefficient: < 1.6E-03
log Pow: < -2.8
Standard deviation: 0.00039

ANION:
Partition coefficient: 4.5E-03
log Pow: -2.4
Standard deviation: 0.0048
Conclusions:
The partition of the test material has been determined to be log Pow: < -2.8 based on the cation and log Pow: -2.4 based on the anion.
Executive summary:

The partition of the test material has been determined in accordance to the standardised guideline OECD 107, under GLP conditions as log Pow: < -2.8 based on cation and log Pow: -2.4 based on anion.

Description of key information

The partition of the test material has been determined in accordance to the standardised guideline OECD 107, under GLP conditions as log Pow: < -2.8 based on cation and log Pow : -2.4 based on anion.

Key value for chemical safety assessment

Log Kow (Log Pow):
-2.8
at the temperature of:
20 °C

Additional information