Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The three reported studies are summarised in the table below.

 

Reference

Study Type

Guideline

GLP

Result

CTL/P/3798

Ames test

OECD 471/472

Yes

Negative

CTL/P/4001

Chromosome Aberration

OECD 473

Yes

Negative

CTL/P/4801

Mouse Lymphoma

OECD 476/ EPA OPPTS 870.5300

Yes

Negative

 


Short description of key information:
Three study reports were available, all present negative results therefore no classification is required.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The conclusion from the three studies reported is that L-2 -Chloropropionic acid is not mutagenic and no classification regarding genetic toxicity is required.