Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
skin sensitisation: in vitro
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a strong acid (pH ≤2.0) or base (pH =>11.5)
Endpoint conclusion
Additional information:

Annex VII of Regulation (EC) 1907/2006 states that in vivo testing of the substance for skin sensitisation does not need to be conducted if 'the substance is a strong acid (pH<2.0) or base (pH>11.5)'. The pH of a 1%v/v solution of L-2-Chloropropionic acid in water was measured to be pH 1.83, therefore a skin sensitisation study is not required.

Justification for classification or non-classification