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Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation: in vitro
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a strong acid (pH ≤2.0) or base (pH =>11.5)
Endpoint conclusion
Additional information:

Annex VII of Regulation (EC) 1907/2006 states that in vivo testing of the substance for skin sensitisation does not need to be conducted if 'the substance is a strong acid (pH<2.0) or base (pH>11.5)'. The pH of a 1%v/v solution of L-2-Chloropropionic acid in water was measured to be pH 1.83, therefore a skin sensitisation study is not required.

Justification for classification or non-classification

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